Lil’ Brimstone – 4 soul hearts, 2 pennies, 1 nickel, 1 bomb.

Guardian Angel – 3 red hearts, 1 eternal heart, 1 penny, 2 keys, 1 bomb.

Incubus – 1 red heart, 4 soul hearts, 1 black heart, 1 key, 1 rune/soul.

These familiars are going to help carry your run, however they are not the cheapest so if you have crafted Birthright, you may be lucky enough to get these!

Robo-Baby – 4 red hearts, 2 pennies, 2 keys.

Brother Bobby – 1 soul heart, 4 pennies, 1 key, 2 bombs.

Little Steven – 1 red heart, 1 soul heart, 1 penny, 1 key, 4 bombs.

These familiars are the cheapest, easiest to obtain! This is where the guide is flexible, you can either build up the army or focus on building up your tear rate, damage or range! Depths), you’re going to want to build your army further, crafting as many cheap familiars as possible (or more expensive one’s, depending on your luck). That’s your DPS set up for now! You can steamroll early-game bosses efficiently with the familiars and triple shot you just gained, alongside your supportive frozen friends! Mid-GameĪs you go further into mid-game (i.e.

2 red hearts, 2 soul hearts, 3 pennies, 1 bomb OR 3 pennies, 4 bombs, 1 pill.

1 soul heart, 2 pennies, 5 bombs OR 2 red hearts, 1 penny, 1 nickel, 2 keys, 2 bombsĪnother Optional but highly recommended item is Birthright, as it increases the amount of drops from item pedestals, i.e.

This is entirely Optional but highly recommended, craft BFFs!: Once you are Conjoined, craft yourself a Tractor Beam: The easiest and strongest familiar to craft is the Freezer Baby, costing only:

You are going to need 3 familiars to get the Conjoined Transformation. Okay, first off you need to start your run as Tainted Cain.

Useful Synergies: Some great trinkets and items to aid your army further.

Switching to Other Characters: Utilising The Clicker, also telling you how not to break the game and get stuck as Tainted Forgotten.

Late-Game: Do what you need to do basically, a useless section of encouragement.

Mid-Game: Crafting more familiars, building your army to slay whatever enters your path.

Early Game: Crafting 3 Freezer Babies, 1 Tractor Beam, and a whole lot of pain.

This strategy will allow you to become Lilith as Tainted Cain, adopting her love for familiars and using said familiars to form an army of unstoppable anguish, hence Cillith (Lilith + Cain + Kill = Cillith).

Binding of isaac rebirth strategy